Open hardware facilitated by tools such as 3D printers is transforming science. Two sites – one in Virginia and one in Kenya – are collaborating with the Make to Learn Laboratory at the University of Virginia to extend open science tools to schools. Students in the National Society of Black Engineers (NSBE) Jr. chapter at Albemarle High School (AHS) are designing 3D-printed microscopes that are being replicated in the Winam Fabrication Laboratory (FabLab) in Kenya. Kenyan students are designing a 3D-printed microcentrifuge that is being replicated in Virginia. This program of reciprocal innovation is strengthening science in schools at both sites.